The SpaceNavigator is the officially supported product on the Mac OS X platform.
The interface we provide will display a SpaceNavigator product. Only two buttons will be available for use and reprogrammability.
There are no drivers listed on our Driver Download Page for the SpacePilot nor for the SpacePilot PRO.
You will want to check under the Solutions Menu, for All Supported Applications and the MAC OS X Tab for a listing of the applications and versions that make use of those devices.
I do not believe the SpacePilot PRO works on the Mac Platform.
I would recommend the SpaceNavigator for working with programs on a MacIntosh.
The more things change, the more they remain the same. ; ^ )