I'm sorry I forgot something:
The containing directory "3DxWare" just has drwx------ (0600). It should be drwxr-xr-x (chmod 0655) so that normal users can access the directory with the config files (after being started 3dxsrv switches to the currently logged in user), which is normally an unprivileged user.
If it still doesn't work and you don't mind, please set the permissions to 0644. This is what I have by default. Also I've the 3dxsrv binary set to 0655.
Please let me know what your results are!